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2-Chloro-4-nitrophenyl a-L-fucopyranoside
| CAS No: | 157843-41-9 |
| Product Code: | EC05990 |
| Chemical Formula: | |
| Molecular Weight: | 319.69 |
| Product Structure
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| Pack Size | Pack Price | Hazardous Surcharge | Special Packaging | Number of Packs |
| 50mg | $40.00 £28.00 €32.50 | Not Applicable Not Applicable Not Applicable Not Applicable Not Applicable | Not Applicable Not Applicable Not Applicable Not Applicable Not Applicable | |
| 100mg | $60.00 £42.00 €49.00 | Not Applicable Not Applicable Not Applicable Not Applicable Not Applicable | Not Applicable Not Applicable Not Applicable Not Applicable Not Applicable | |
| 250mg | $100.00 £70.00 €80.00 | Not Applicable Not Applicable Not Applicable Not Applicable Not Applicable | Not Applicable Not Applicable Not Applicable Not Applicable Not Applicable | |
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2-Chloro-4-nitrophenyl a-L-fucopyranoside
2-Chloro-4-nitrophenyl α -L-fucopyranoside (CNPF) is a substrate for the enzyme α -L-fucosidase (AFU). CNPF is hydrolysed by α-L-fucosidase to fucose and 2-chloro-4-nitrophenol. The levels of AFU in human serum are a useful marker for diagnosing hepatocellular carcinoma (HCC), being significantly higher in patients with HCC than those with cirrhosis, other malignant neoplasms or control subjects.1 A highly sensitive and specific assay monitoring the hydrolysis of CNPF by AFU has been developed for use in the early diagnosis of HCC.2
Refs:
1. MG Giardina et al, Cancer, 1992, 70, 1044.
2. JJ Wang et al, Clin. Chim. Acta, 2004, 347, 103