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2-Chloro-4-nitrophenyl a-L-fucopyranoside
| CAS No: | 157843-41-9 |
| Product Code: | EC05990 |
| MDL No: | MFCD04972056 |
| Chemical Formula: | |
| Molecular Weight: | 319.69 |
| Product Structure
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Click to load specification |
| Pack Size | Pack Price | Hazardous Surcharge | Special Packaging | Number of Packs |
| 50mg | $40.00 £26.00 €33.00 | Not Applicable Not Applicable Not Applicable | Not Applicable Not Applicable Not Applicable | |
| 100mg | $60.00 £39.00 €50.00 | Not Applicable Not Applicable Not Applicable | Not Applicable Not Applicable Not Applicable | |
| 250mg | $100.00 £65.00 €82.50 | Not Applicable Not Applicable Not Applicable | Not Applicable Not Applicable Not Applicable | |
500mg 500mg 500mg | $150.00 £100.00 €125.00 | Not Applicable Not Applicable Not Applicable | Not Applicable Not Applicable Not Applicable | |
1g 1g 1g | $250.00 £162.50 €207.50 | Not Applicable Not Applicable Not Applicable | Not Applicable Not Applicable Not Applicable | |
Custom Pack  |
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| | Not Applicable Not Applicable Not Applicable | Not Applicable Not Applicable Not Applicable | Enter a pack size. |
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2-Chloro-4-nitrophenyl a-L-fucopyranoside
2-Chloro-4-nitrophenyl α -L-fucopyranoside (CNPF) is a substrate for the enzyme α -L-fucosidase (AFU). CNPF is hydrolysed by α-L-fucosidase to fucose and 2-chloro-4-nitrophenol. The levels of AFU in human serum are a useful marker for diagnosing hepatocellular carcinoma (HCC), being significantly higher in patients with HCC than those with cirrhosis, other malignant neoplasms or control subjects.1 A highly sensitive and specific assay monitoring the hydrolysis of CNPF by AFU has been developed for use in the early diagnosis of HCC.2
Refs:
1. MG Giardina et al, Cancer, 1992, 70, 1044.
2. JJ Wang et al, Clin. Chim. Acta, 2004, 347, 103