Carbosynth products are widely used by scientific community and cited in peer-reviewed, high impact journals on a daily basis. We highlight 3 top publications every month but you can find a full list of papers citing our molecules here.
Inhibitor of ERK 1/2, SCH 772984, was used to demonstrate involvement of the ERK pathway in neprilysin expression.
Kinetic studies on saponins from Zolfino bean reveal their ability to inhibit aldose reductase.
Human hepatocyte-like cell lines were infected with Zika virus and treated with RNA polymerase inhibitors.
Biochemical studies investigating uptake and catabolism of MurNAc and its role in cell wall metabolism
Patients with Marinesco-Sjögren-like syndrome were tested for the enzymatic activity of GBA2
Anti-angiogenic effect of sialyllactose is mediated by suppressing VEGFR-2 activation
T-synthase is a key enzyme for O-glycan synthesis and can be detected with fluorescent assay using 4MU-conjugated donor.
Finasteride and dutasteride reduced adverse effects of anti-parkinsonian therapy.
Oridonin and forskolin reduced neuroinflammation and restored behavioural deficits in Alzheimer's disease model.
An alternative route of synthesis using FAC from Carbosynth (ND08343).
Inhibiting lactate importer MCT1 reverses lactate-induced resistance in cancer cells.
Inhibitors that specifically target the polyol pathway are desirable, indicated by preferential reduction in L-idose (MI04205)
Viral envelope N-glycans interact with L-selectin on central memory T cells.
Bacterial toxin scavenging particles displaying GM1 ganglioside efficiently attenuate cholera toxin symptoms.
O-GlcNAc cycling enzymes are mutually controlled at the transcriptional level.
Lactulose (OL03995) as substrate for synthesis of HMO-mimics via the one-pot two-enzyme system
The structure of BKV in complex with GT1b (OO16323) will aid in developing new therapies.
SN 38 (FE29579) and biotin in a theranostic compound detects and treats hypoxic solid tumors.
E. coli overgrowth depends on free sialidases secreted by other components of gut microbiome.
Iduronate-2-sulfatase delivery to brain corrects MPS II symptoms.
Adapter is linked to the 3' end of ssDNA via click reaction and then converted into dsDNA.
The sensitivity of avian influenza A (H5N1) viruses, of clade 2.1, to NAIs was tested.
Transport and metabolism of LacNAC, from Carbosynth, by L. casei.
Temozolomide causes defects in DNA mismatch repair mechanism.
LacNAc capping causes hyperproliferation of stem cells in crypts.
JQ1 was used to investigate the role of BET-induced transcriptional regulation by BRD2,3,4 and BRDT.
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