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OL05009

a-Lactose monohydrate

An α-anomer, obtained by crystallization at low temperature, can be dehydrated to stable form above 130°C or an unstable (hygroscopic) form at lower temperatures. An example of the applications for α-Lactose monohydrate is in dry powder inhalers.  These are devices that deliver medication to the lung in the form of a dry powder generating an aerosol directly from the drug powder or mixture, using an excipient such as lactose monohydrate.

Technical Data

CAS No: 5989-81-1
Synonyms: 4-O-b-D-Galactopyranosyl-a-D-glucopyranose monohydrate
Product Code: OL05009
MDL No: MFCD00150747
Chemical Formula: C12H22O11·H2O
Molecular Weight: 360.31

References


  • Wong DY et al (1988). Deformation of alpha-lactose monohydrate and anhydrous alpha-lactose monocrystals. Drug Dev Ind Pharm 14:2109-2126.
  • Nidhi B et al (2016). Prophylaxis and Prevention of Heart Attack by Pulmonary Delivery of Aspirin by Dry Powder Inhaler. International Journal of Pharmacy & Life Sciences 7(5):5047-5050.

Solubility

Stability

Further Information


Datasheets

Specification: View
MSDS: View

CAS No:
5989-81-1
Synonyms:
4-O-b-D-Galactopyranosyl-a-D-glucopyranose monohydrate
MDL No:
MFCD00150747
Chemical Formula:
Molecular Weight:
360.31
Product Structure
References:
1. Wong DY et al (1988). Deformation of alpha-lactose monohydrate and anhydrous alpha-lactose monocrystals. Drug Dev Ind Pharm 14:2109-2126.
2. Nidhi B et al (2016). Prophylaxis and Prevention of Heart Attack by Pulmonary Delivery of Aspirin by Dry Powder Inhaler. International Journal of Pharmacy & Life Sciences 7(5):5047-5050.
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