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BH167270
BIO-X

H 151 NEW

A potent inhibitor of STING protein (stimulator of interferon genes), a protein that partakes in intracellular DNA sensing pathway.  H 151 blocks palmitoylation of STING, which is required for the formation of multimeric complexes for recruiting downstream signalling molecules. Inhibition of STING by H 151 reduces pro-inflammatory cytokine synthesis.

Technical Data

CAS No: 941987-60-6
Synonyms: 1-​(4-​Ethylphenyl)​-​3-​(1H-​indol-​3-​yl)​urea
Product Code: BH167270
Chemical Formula: C17H17N3O
Molecular Weight: 279.34

References


  • Haag SM et al (2018). Targeting STING with covalent small-molecule inhibitors. Nature 559(7713):269-273.

Solubility

Stability

Further Information


Datasheets

Specification: View
MSDS: View

H 151 - Bio-X

CAS No:
941987-60-6
Synonyms:
1-​(4-​Ethylphenyl)​-​3-​(1H-​indol-​3-​yl)​urea
Chemical Formula:
Molecular Weight:
279.34
Product Structure
References:
1. Haag SM et al (2018). Targeting STING with covalent small-molecule inhibitors. Nature 559(7713):269-273.
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