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BL167287
BIO-X

LIT 927

An orally active neutraligand of chemokine CXCL12. Has anti-inflammatory action in murine model of allergic airway hypereosinophilia, by reducing eosinophil recruitment.  Unlike other CXCL12 neutraligands, LIT 927 is not a Michael acceptor. This compound can be a pharmacological tool for studying the functions of the CXCL12-CXCR4 axis.

Technical Data

CAS No: 2172879-52-4
Product Code: BL167287
Chemical Formula:

References


  • Regenass P et al (2018). Discovery of a Locally and Orally Active CXCL12 Neutraligand (LIT-927) with Anti-inflammatory Effect in a Murine Model of Allergic Airway Hypereosinophilia. J Med Chem 61(17):7671-7686.

Solubility

Stability

Further Information


Datasheets


LIT 927 - Bio-X

CAS No:
2172879-52-4
Chemical Formula:
Molecular Weight:
Product Structure
References:
1. Regenass P et al (2018). Discovery of a Locally and Orally Active CXCL12 Neutraligand (LIT-927) with Anti-inflammatory Effect in a Murine Model of Allergic Airway Hypereosinophilia. J Med Chem 61(17):7671-7686.

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