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BF160700
BIO-X

FG 7142

Partial inverse agonist of benzodiazepine sites of the GABAA receptors with anxiogenic properties. FG 7142 is a pharmacological stressor which generates anxiety in humans and in experimental animals such as rhesus monkeys and rodents. FG 7142 also reduces food intake and frequency of feeding in male and female rats.

Technical Data

CAS No: 78538-74-6
Synonyms: N-Methyl-b-carboline-3-carboxamide
Product Code: BF160700
Chemical Formula: C13H11N3O
Molecular Weight: 225.25

References


  • Kurumaji and Nishikawa, 2012. An anxiogenic drug, FG 7142, induced an increase in mRNA of Btg2 and Adamts1 in the hippocampus of adult mice. Behavioural and Brain Functions 8:43.
  • Cottone et al (2006). FG 7142 Specifically Reduces Meal Size and the Rate and Regularity of Sustained Feeding in Female Rats: Evidence that Benzodiazepine Inverse Agonists Reduce Food Palatability. Nature 32:1069–1081.

Solubility

Stability

Further Information


Datasheets

Specification: View
MSDS: View

CAS No:
78538-74-6
Synonyms:
N-Methyl-b-carboline-3-carboxamide
Chemical Formula:
Molecular Weight:
225.25
Product Structure
References:
1. Kurumaji and Nishikawa, 2012. An anxiogenic drug, FG 7142, induced an increase in mRNA of Btg2 and Adamts1 in the hippocampus of adult mice. Behavioural and Brain Functions 8:43.
2. Cottone et al (2006). FG 7142 Specifically Reduces Meal Size and the Rate and Regularity of Sustained Feeding in Female Rats: Evidence that Benzodiazepine Inverse Agonists Reduce Food Palatability. Nature 32:1069–1081.
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