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BE162758

Epiblastin A - Bio-X NEW

Inhibits CK1 α, δ and ε isoforms (IC50 values = 8.9, 0.5, and 4.7 ìM, respectively). Induces reprogramming of epiblast-derived stem cells (EpiSCs) to embryonic stem cells (ESCs). If the latter express Oct4-GFP, the compound can be used as a tool to study this signaling pathway.

Technical Data

CAS No: 16470-02-3
Synonyms: AUE; 6-(3-Chloro-phenyl)-pteridine-2,4,7-triamine
Product Code: BE162758
Chemical Formula: C12H10ClN7
Molecular Weight: 287.71

References


  • Ursu A et al (2016). Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1. Cell Chem Biol 23(4):494-507.

Solubility

Stability

Further Information


Datasheets

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MSDS: View

Epiblastin A - Bio-X

CAS No:
16470-02-3
Synonyms:
AUE
6-(3-Chloro-phenyl)-pteridine-2,4,7-triamine
Chemical Formula:
Molecular Weight:
287.71
Product Structure
References:
1. Ursu A et al (2016). Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1. Cell Chem Biol 23(4):494-507.
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