Specific inhibitor of 8-oxoguanine DNA glycosylase OGG1 with IC50 of 0.22 μM. OGG1 is a key enzyme in DNA repair mechanism called base excision repair (BER). The compound inhibits the hydrolysis of glycosidic bond required for the excision of 8-oxoguanine from double stranded DNA, which leads to accumulation of mutations. It has been proposed as monotherapy for certain types of cancers. It may also be used as adjuvant for cancer therapy as it was seen to sensitize tumors for chemotherapy.