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OF63366

Fucosyl-GM1 ganglioside

Monosialylated glycosphingolipid with an α1,2-fucosylated galactose at the nonreducing end. The moluecule is minimally expressed in healthy tissues but has high prevalence in some tumours such as small cell lung cancer (SCLC). Fucosyl-GM1 ganglioside is a potential tumour marker for SCLC and a potential antigen target for immunotherapy.

Technical Data

CAS No: 71812-11-8
Synonyms: Fucosylated monosialoganglioside GM1
Product Code: OF63366
Chemical Formula: C79H141N3O35
Molecular Weight: 1692.96

References


  • Tokuda et al (2006). Genetic mechanisms for the synthesis of fucosyl GM1 in small cell lung cancer cell lines. Glycobiology 16(10):916–925.
  • Drovsholm et al (1994). Fucosyl-GM1 in small-cell lung cancer. A comparison with the tumour marker neuron-specific enolase. Annals of Oncology 5(7):623-6.

Solubility

Stability

Further Information


Datasheets

Specification: View
MSDS: View

CAS No:
71812-11-8
Synonyms:
Fucosylated monosialoganglioside GM1
Chemical Formula:
Molecular Weight:
1692.96
Product Structure
References:
1. Tokuda et al (2006). Genetic mechanisms for the synthesis of fucosyl GM1 in small cell lung cancer cell lines. Glycobiology 16(10):916–925.
2. Drovsholm et al (1994). Fucosyl-GM1 in small-cell lung cancer. A comparison with the tumour marker neuron-specific enolase. Annals of Oncology 5(7):623-6.
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