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MD04977

2-Deoxy-D-ribose

Used in synthetic organic chemistry and natural product synthesis. Induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. It is used for synthesis of optically active dipyrrolyl alkanols from pyrroles on the surface of montmorillonite KSF clay.

Technical Data

CAS No: 533-67-5
Synonyms: Thyminose; 2-Deoxy-D-erythropentose; 2-Deoxy-D-arabinose
Product Code: MD04977
MDL No: MFCD00135904
Chemical Formula: C5H10O4
Molecular Weight: 134.13

Literature

References
  • Dueholm KL et al (1992). Synthesis of 3'-alkylthio-2',3'-dideoxy nucleosides with potential anti-HIV activity from 2-deoxy-D-ribose, using a phosphorus pentoxide reagent. Arch Pharm (Weinheim) 325(9): 597-601.
  • Quesada-Moreno MM et al (2013). Conformational preference and chiroptical response of carbohydrates D-ribose and 2-deoxy-D-ribose in aqueous and solid phases. J Phys Chem B 117(47):14599-614.
  • Koh G et al (2015). Intracellular glutathione production, but not protein glycation, underlies the protective effects of captopril against 2-deoxy-D-ribose-induced β-cell damage. Mol Med Rep 12(4):5314-20.

Solubility

Stability

Datasheets

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Technical Bulletin: View

2-Deoxy-D-ribose

CAS No:
533-67-5
Synonyms:
Thyminose
2-Deoxy-D-erythropentose
2-Deoxy-D-arabinose
MDL No:
MFCD00135904
Chemical Formula:
Molecular Weight:
134.13
Product Structure
References:
1. Dueholm KL et al (1992). Synthesis of 3'-alkylthio-2',3'-dideoxy nucleosides with potential anti-HIV activity from 2-deoxy-D-ribose, using a phosphorus pentoxide reagent. Arch Pharm (Weinheim) 325(9): 597-601.
2. Quesada-Moreno MM et al (2013). Conformational preference and chiroptical response of carbohydrates D-ribose and 2-deoxy-D-ribose in aqueous and solid phases. J Phys Chem B 117(47):14599-614.
3. Koh G et al (2015). Intracellular glutathione production, but not protein glycation, underlies the protective effects of captopril against 2-deoxy-D-ribose-induced β-cell damage. Mol Med Rep 12(4):5314-20.
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