Availability
0
Your Basket is Empty
OO16323

GT1b-Oligosaccharide

Oligosaccharide moiety from the trisialylated glycosphingolipid GT1b of b-series, which is one of the major gangliosides in neuronal and glial membranes. The compound interacts with myelin-associated glycoprotein (MAG) and is essential for long-term axon-myelin stability. GT1b ganglioside also acts as receptor for bacterial toxins such as tetanus and botulinum toxins as well as for viruses, a few examples include Merkel cell polyomavirus, JC virus, BK virus, norovirus and others.

Technical Data

CAS No: 75663-36-4
Product Code: OO16323
Chemical Formula: C59H96N4O45
Molecular Weight: 1581.39

References


  • Yu et al (2012). Functional roles of gangliosides in neurodevelopment: An overview of recent advances. Neurochemistry Research 37:1230–1244.
  • Low et al (2006). Identification of Gangliosides GD1b and GT1b as Receptors for BK Virus. Journal of Virology 80(3):1361-6.
  • Brunger and Rummel (2009). Receptor and substrate interactions of clostridial neurotoxins. Toxicon 54:550–560.
  • Nakamura et al (2012). Unique biological activity of botulinum D/C mosaic neurotoxin in murine species. Infection and Immunity 80:2886–2893.

Solubility

Stability

Further Information


Datasheets

Specification: View
MSDS: View

CAS No:
75663-36-4
Chemical Formula:
Molecular Weight:
1581.39
Product Structure
References:
1. Yu et al (2012). Functional roles of gangliosides in neurodevelopment: An overview of recent advances. Neurochemistry Research 37:1230–1244.
2. Low et al (2006). Identification of Gangliosides GD1b and GT1b as Receptors for BK Virus. Journal of Virology 80(3):1361-6.
3. Brunger and Rummel (2009). Receptor and substrate interactions of clostridial neurotoxins. Toxicon 54:550–560.
4. Nakamura et al (2012). Unique biological activity of botulinum D/C mosaic neurotoxin in murine species. Infection and Immunity 80:2886–2893.
Click for Specification
Click for MSDS

For requirements greater than the catalogue prepacks email: enquiries@carbosynth.com

Custom Synthesis

For custom synthesis or special requests email: enquiries@carbosynth.com, call +44 (0)1635 578444 or fill out our contact form

Please Wait...