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BZ162628
BIO-X

ZD 7288

Blocks hyperpolarization-activated cyclic nucleotide-gated (HCN) channels

Technical Data

CAS No: 133059-99-1
Synonyms: N-Ethyl-1,6-dihydro-1,2-dimethyl-6-(methylimino)-N-phenyl-4-pyrimidinamine HCl
Product Code: BZ162628
MDL No: MFCD29919955
Chemical Formula: C15H21ClN4
Molecular Weight: 292.81

References


  • BoSmith et al (1993) Inhibitory actions of ZENECA ZD7288 on whole cell hyperpolarization activated inward current (If) in guinea-pig dissociated sinoatrial node cells. Br.J.Pharmacol. 110 343
  • Green et al (1996) Pharmacological characterization of the inwardly rectifying current in the smooth muscle cells of the rat bladder. Br.J.Pharmacol. 119 1509
  • Harris and Constanti (1995) Mechanism of block by ZD7288 of the hyperpolarization-activated inward rectifying current in guinea-pig substantia nigra neurons in vitro. J.Neurophysiol. 74 2366

Solubility

Stability

Further Information


Datasheets


CAS No:
133059-99-1
Synonyms:
N-Ethyl-1,6-dihydro-1,2-dimethyl-6-(methylimino)-N-phenyl-4-pyrimidinamine HCl
MDL No:
MFCD29919955
Chemical Formula:
Molecular Weight:
292.81
Product Structure
References:
1. BoSmith et al (1993) Inhibitory actions of ZENECA ZD7288 on whole cell hyperpolarization activated inward current (If) in guinea-pig dissociated sinoatrial node cells. Br.J.Pharmacol. 110 343
2. Green et al (1996) Pharmacological characterization of the inwardly rectifying current in the smooth muscle cells of the rat bladder. Br.J.Pharmacol. 119 1509
3. Harris and Constanti (1995) Mechanism of block by ZD7288 of the hyperpolarization-activated inward rectifying current in guinea-pig substantia nigra neurons in vitro. J.Neurophysiol. 74 2366

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