Inhibition of acetylcholinesterase (AChE) leads to accumulation of acetylcholine in the synaptic cleft causing overstimulation of nicotinic and muscarinic receptors and alteration for the neurotransmission signal. Molecules that can inhibit acetylcholinesterase have important pharmacological and toxicological properties. For example reversible inhibitors of AChE are commonly employed for the treatment of cognitive and neurodegenerative disorders (Alzheimer’s disease), while irreversible inhibitors are used as pesticides, insecticides and nerve agents. Corydaline is a well known alkaloid found in the plant Corydalis yanhusuo which displays significant AChe inhibition properties. Recently, (Biological & Pharmaceutical Bulletin, 2010, 958-62) it was found that Corydaline can also accelerate gastric emptying and gastric relaxation in animal model.