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BA167271
BIO-X

ASP 6432

Potent antagonist of type 1 receptor lysophosphatidic acid (LPA1), selective over other LPA subtypes at least by ten-fold. Blocks LPA-induced contraction in urethra and prostate, as well as proliferation of prostatic stromal cells. These findings indicate a potential use of ASP 6432 for the treatment of lower urinary tract symptoms and benign prostatic hyperplasia (LUTS/BPH).

Technical Data

CAS No: 1282549-08-9
Product Code: BA167271
Chemical Formula: C26H31N4O6S2·K
Molecular Weight: 598.78

References


  • Sakamoto K et al (2018). Effect of ASP6432, a Novel Type 1 Lysophosphatidic Acid Receptor Antagonist, on Urethral Function and Prostate Cell Proliferation. J Pharmacol Exp Ther 366(2):390-396.

Solubility

Stability

Further Information


Datasheets


ASP 6432 - Bio-X

CAS No:
1282549-08-9
Chemical Formula:
Molecular Weight:
598.78
Product Structure
References:
1. Sakamoto K et al (2018). Effect of ASP6432, a Novel Type 1 Lysophosphatidic Acid Receptor Antagonist, on Urethral Function and Prostate Cell Proliferation. J Pharmacol Exp Ther 366(2):390-396.

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