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Research & Development
FP10637

Paclitaxel

Tubulin ligand which promotes microtubule assembly and stabilises microtubule cytoskeleton against depolymerisation. The compound has anti-tumoral activity since its interference with cytoskeleton dynamics affects the assembly of mitotic spindle, segregation of chromosomes, cell division and blocks the cell cycle in G1 or M phase. The compound is also used for the purification of tubulin or microtubule-associated proteins.

Technical Data

CAS No: 33069-62-4
Synonyms: Taxol
Product Code: FP10637
MDL No: MFCD00869953
Chemical Formula: C47H51NO14
Molecular Weight: 853.91

References


  • Arnal and Wade (1995). How does taxol stabilize microtubules? Current Biology 5(8):900-908.
  • Horwitz (1994). Taxol (paclitaxel): mechanisms of action. Annals of Oncology 5 Suppl 6 S3-6.

Solubility

Stability

Further Information


Datasheets

Specification: View
MSDS: View

CAS No:
33069-62-4
Synonyms:
Taxol
MDL No:
MFCD00869953
Chemical Formula:
Molecular Weight:
853.91
Product Structure
References:
1. Arnal and Wade (1995). How does taxol stabilize microtubules? Current Biology 5(8):900-908.
2. Horwitz (1994). Taxol (paclitaxel): mechanisms of action. Annals of Oncology 5 Suppl 6 S3-6.
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