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BA166488
BIO-X

(R)-ADX 47273

Positive allosteric modulator of the metabotropic glutamate receptor mGluR5 with EC50 in submicromolar range. The compound is able to increase mGluR5 function in vitro and in vivo. A study showed that ADX-47273 enhanced fear extinction learning as well as improved reversal learning in experimental animals.

Technical Data

CAS No: 851881-59-9
Product Code: BA166488
MDL No: MFCD31692421
Chemical Formula: C20H17F2N3O2
Molecular Weight: 369.36

References


  • Xu et al (2013). Potentiating mGluR5 function with a positive allosteric modulator enhances adaptive learning. Learning and Memory 20(8):438–445.

Solubility

Stability

Further Information


Datasheets

Specification: View
MSDS: View

CAS No:
851881-59-9
MDL No:
MFCD31692421
Chemical Formula:
Molecular Weight:
369.36
Product Structure
References:
1. Xu et al (2013). Potentiating mGluR5 function with a positive allosteric modulator enhances adaptive learning. Learning and Memory 20(8):438–445.
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