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FA17962

Aprepitant

Antagonist of neurokinin-1 receptor; anti-emetic

Technical Data

CAS No: 170729-80-3
Synonyms: 5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one; Emend; L 754030
Product Code: FA17962
MDL No: MFCD08277635
Chemical Formula: C23H21F7N4O3
Molecular Weight: 534.43

References


  • Hale, J.J., et al., J. Med. Chem., 41, 4607 (1998)
  • Campos, D., et al., J. Clin. Oncol., 19, 1759 (2001)
  • Van Belle, S., et al., Cancer, 94, 3032 (2002)
  • Majumdar, A.K., et al., J. Clin. Pharmacol., 46, 291 (2006)

Solubility

Stability

Further Information


Datasheets

Specification: View
MSDS: View

CAS No:
170729-80-3
Synonyms:
5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one
Emend
L 754030
MDL No:
MFCD08277635
Chemical Formula:
Molecular Weight:
534.43
Product Structure
References:
1. Hale, J.J., et al., J. Med. Chem., 41, 4607 (1998)
2. Campos, D., et al., J. Clin. Oncol., 19, 1759 (2001)
3. Van Belle, S., et al., Cancer, 94, 3032 (2002)
4. Majumdar, A.K., et al., J. Clin. Pharmacol., 46, 291 (2006)
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