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BB162589

BRD 6989 - Bio-X

A small molecule inhibitor with high selectivity for CDK8 over CDK19. Increases IL-10 production in stimulated human and murine macrophages and dendritic cells. Modulatory action on inflammatory responses has therapeutic potential.

Technical Data

CAS No: 642008-81-9
Product Code: BB162589
Chemical Formula: C16H16N4
Molecular Weight: 264.33

Literature


  • Johannessen L et al (2017). Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cells. Nat Chem Biol 13(10):1102-1108.

Solubility

Stability

Further Information


Datasheets

Specification: View
MSDS: View

BRD 6989 - Bio-X

CAS No:
642008-81-9
Chemical Formula:
Molecular Weight:
264.33
Product Structure
References:
1. Johannessen L et al (2017). Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cells. Nat Chem Biol 13(10):1102-1108.
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