Availability
0
Your Basket is Empty
OS04058

3'-Sialyl Lewis X

Binding ligand for endothelial adhesion molecule E-selectin

Technical Data

CAS No: 98603-84-0
Synonyms: NeuNAc-a2-3Gal-b1-4(Fuc-a1-3)GlcNAc
Product Code: OS04058
MDL No: MFCD00270073
Chemical Formula: C31H52N2O23
Molecular Weight: 820.74

Literature


  • Ameno, S et al (2001). Lewis and Secretor gene effects on Lewis antigen and postnatal development of Lewis blood type. Biol Neonate 79(2): 91-6., Roy, R et al (1987). Low kidney graft survival in Lewis negative patients after regrafting and newer matching schemes for Lewis. Transplant Proc 19(6):4498-502.
  • Chandrasekaran EV et al (1996). Characterization of the specificities of human blood group H gene-specified alpha 1,2-L-fucosyltransferase toward sulfated/sialylated/fucosylated acceptors: evidence for an inverse relationship between alpha 1,2-L-fucosylation of Gal and alpha 1,6-L-fucosylation of asparagine-linked GlcNAc. Biochem 35(27):8914-24., Stanley and Cummings. (2008). Structures Common to Different Glycans in Essentials of Glycobiology. 2nd Ed, Edited by Ajit Varki,Cold Spring Harbor Laboratory Press, USA.
  • Falk, P et al (1993). An in vitro adherence assay reveals that Helicobacter pylori exhibits cell lineage-specific tropism in the human gastric epithelium. Proc Nat Acad Sci 90(5): 2035-2039., Takada A et al (1993). Contribution of Carbohydrate Antigens Sialyl Lewis A and Sialyl Lewis X to Adhesion of Human Cancer Cells to Vascular Endothelium. Cancer Res 53(2): 354.
  • Hakomori, S et al (1986). Tumor-associated glycolipid antigens, their metabolism and organization. Chem Phys Lipids 42(1-3):209-33.
  • Marcus, DM and Cass, LE (1969). Glycosphingolipids with Lewis blood group activity: uptake by human erythrocytes. Science 164(3879):553-5.

Solubility

Stability

Further Information


Datasheets

Specification: View
MSDS: View
Technical Bulletin: View

3'-Sialyl Lewis X

CAS No:
98603-84-0
Synonyms:
NeuNAc-a2-3Gal-b1-4(Fuc-a1-3)GlcNAc
MDL No:
MFCD00270073
Chemical Formula:
Molecular Weight:
820.74
Product Structure
References:
1. Ameno, S et al (2001). Lewis and Secretor gene effects on Lewis antigen and postnatal development of Lewis blood type. Biol Neonate 79(2): 91-6., Roy, R et al (1987). Low kidney graft survival in Lewis negative patients after regrafting and newer matching schemes for Lewis. Transplant Proc 19(6):4498-502.
2. Chandrasekaran EV et al (1996). Characterization of the specificities of human blood group H gene-specified alpha 1,2-L-fucosyltransferase toward sulfated/sialylated/fucosylated acceptors: evidence for an inverse relationship between alpha 1,2-L-fucosylation of Gal and alpha 1,6-L-fucosylation of asparagine-linked GlcNAc. Biochem 35(27):8914-24., Stanley and Cummings. (2008). Structures Common to Different Glycans in Essentials of Glycobiology. 2nd Ed, Edited by Ajit Varki,Cold Spring Harbor Laboratory Press, USA.
3. Falk, P et al (1993). An in vitro adherence assay reveals that Helicobacter pylori exhibits cell lineage-specific tropism in the human gastric epithelium. Proc Nat Acad Sci 90(5): 2035-2039., Takada A et al (1993). Contribution of Carbohydrate Antigens Sialyl Lewis A and Sialyl Lewis X to Adhesion of Human Cancer Cells to Vascular Endothelium. Cancer Res 53(2): 354.
4. Hakomori, S et al (1986). Tumor-associated glycolipid antigens, their metabolism and organization. Chem Phys Lipids 42(1-3):209-33.
5. Marcus, DM and Cass, LE (1969). Glycosphingolipids with Lewis blood group activity: uptake by human erythrocytes. Science 164(3879):553-5.
Click for Specification
Click for MSDS
Click for Technical Bulletin

For requirements greater than the catalogue prepacks email: enquiries@carbosynth.com

Custom Synthesis

For custom synthesis or special requests email: enquiries@carbosynth.com, call +44 (0)1635 578444 or fill out our contact form

Please Wait...