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BM166959
BIO-X

Metarrestin NEW

Inhibits perinuclear compartment, by mediating its disassembly in cancer cell lines. Interacts with translation elongation factor eEF1A2, resulting in disruption of nucleolar structure and inhibition of RNA polymerase (Pol) I transcription. Whilst having mild effects on primary tumors, metarrestin suppresses growth and invasion of metastatic tumors in vivo.

Technical Data

CAS No: 1443414-10-5
Product Code: BM166959
MDL No: MFCD31726173
Chemical Formula: C31H30N4O
Molecular Weight: 474.60

References


  • Frankowski KJ et al (2018). Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis. Sci Transl Med 10(441) pii: eaap8307.

Solubility

Stability

Further Information


Datasheets

Specification: View
MSDS: View

CAS No:
1443414-10-5
MDL No:
MFCD31726173
Chemical Formula:
Molecular Weight:
474.60
Product Structure
References:
1. Frankowski KJ et al (2018). Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis. Sci Transl Med 10(441) pii: eaap8307.
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