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BM166959

Metarrestin - Bio-X

Inhibits perinuclear compartment, by mediating its disassembly in cancer cell lines. Interacts with translation elongation factor eEF1A2, resulting in disruption of nucleolar structure and inhibition of RNA polymerase (Pol) I transcription. Whilst having mild effects on primary tumors, metarrestin suppresses growth and invasion of metastatic tumors in vivo.

Technical Data

CAS No: 1443414-10-5
Product Code: BM166959
Chemical Formula: C31H30N4O
Molecular Weight: 474.60

References


  • Frankowski KJ et al (2018). Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis. Sci Transl Med 10(441) pii: eaap8307.

Solubility

Stability

Further Information


Datasheets


Metarrestin - Bio-X

CAS No:
1443414-10-5
Chemical Formula:
Molecular Weight:
474.60
Product Structure
References:
1. Frankowski KJ et al (2018). Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis. Sci Transl Med 10(441) pii: eaap8307.

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