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FD06273

Diphenylcyclopropenone

A potent hapten used as topical therapy for cutaneous warts, atopic dermatitis and alopecia areata. Efficacy as a single agent for the treatment of cutaneous metastatic melanoma has been reported.

Technical Data

CAS No: 886-38-4
Synonyms: 2,3-Diphenyl-2-cyclopropen-1-one
Product Code: FD06273
MDL No: MFCD00001311
Chemical Formula: C15H10O
Molecular Weight: 206.24

Literature


  • Breslow R et al (1959). The Synthesis of Diphenylcyclopropenone. J Am Chem Soc 81(1):247-248.
  • Damian DL and Thompson JF (2007). Treatment of extensive cutaneous metastatic melanoma with topical diphencyprone. J Am Acad Dermatol 56(5):869-71.
  • Alkhalifah A et al (2010). Alopecia areata update: part II. Treatment. J Am Acad Dermatol 62(2):191-202.
  • Svalgaard JD et al (2014). Systemic immunogenicity of para-Phenylenediamine and Diphenylcyclopropenone: two potent contact allergy-inducing haptens. Immunol Res 58(1):40-50.

Solubility

Stability

Further Information


Datasheets

Specification: View
MSDS: View
Technical Bulletin: View

Diphenylcyclopropenone

CAS No:
886-38-4
Synonyms:
2,3-Diphenyl-2-cyclopropen-1-one
MDL No:
MFCD00001311
Chemical Formula:
Molecular Weight:
206.24
Product Structure
References:
1. Breslow R et al (1959). The Synthesis of Diphenylcyclopropenone. J Am Chem Soc 81(1):247-248.
2. Damian DL and Thompson JF (2007). Treatment of extensive cutaneous metastatic melanoma with topical diphencyprone. J Am Acad Dermatol 56(5):869-71.
3. Alkhalifah A et al (2010). Alopecia areata update: part II. Treatment. J Am Acad Dermatol 62(2):191-202.
4. Svalgaard JD et al (2014). Systemic immunogenicity of para-Phenylenediamine and Diphenylcyclopropenone: two potent contact allergy-inducing haptens. Immunol Res 58(1):40-50.
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