Availability
0
Your Basket is Empty
NA10018
BIO-R

Abacavir

A carbocyclic 2’-deoxyguanosine nucleoside reverse transcriptase (RT) inhibitor with anti-retroviral activity against HIV. Good oral bioavailability, high aqueous solubility and good cerebrospinal fluid penetrance. Synergistic with other nucleoside RT inhibitors such as AZT.

Technical Data

CAS No: 136470-78-5
Product Code: NA10018
MDL No: MFCD08706393
Chemical Formula: C14H18N6O
Molecular Weight: 286.33

Literature

References
  • S M Daluge et al (1997). 1592U89, a novel carbocyclic nucleoside analog with potent, selective anti-human immunodeficiency virus activity. Antimicrob Agents Chemother 41(5): 1082–1093.
  • Mallal S et al (2002). Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir. Lancet 359(9308):727-32.
  • Yuen GJ et al (2008). A review of the pharmacokinetics of abacavir. Clin Pharmacokinet 47(6):351-71.

Solubility

Stability

Datasheets

Specification: View
MSDS: View

Abacavir

CAS No:
136470-78-5
MDL No:
MFCD08706393
Chemical Formula:
Molecular Weight:
286.33
Product Structure
References:
1. S M Daluge et al (1997). 1592U89, a novel carbocyclic nucleoside analog with potent, selective anti-human immunodeficiency virus activity. Antimicrob Agents Chemother 41(5): 1082–1093.
2. Mallal S et al (2002). Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir. Lancet 359(9308):727-32.
3. Yuen GJ et al (2008). A review of the pharmacokinetics of abacavir. Clin Pharmacokinet 47(6):351-71.
Click for Specification
Click for MSDS

For requirements greater than the catalogue prepacks email: enquiries@carbosynth.com

Custom Synthesis

For custom synthesis or special requests email: enquiries@carbosynth.com, call +44 (0)1635 578444 or fill out our contact form

Please Wait...