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MP05328

1,2,3,4,6-Penta-O-galloyl-b-D-glucopyranose NEW

A gallotannin found in plants, with various biological activities. Its anti-cancer effect has been demonstrated in several cancer cell lines, mediated by inhibition of DNA replication, proliferation and angiogenesis. Elicits anti-inflammatory, antioxidative and anti-diabetic effects. Recently, it has been identified as an inhibitor of c-Myc in hepatocellular carcinoma and multiple myeloma cells.

Technical Data

CAS No: 14937-32-7
Synonyms: Pentagalloylglucose; PGG
Product Code: MP05328
MDL No: MFCD03788860
Chemical Formula: C41H32O26
Molecular Weight: 940.68

Literature


  • Zhang, J et al (2009). Anti-cancer, anti-diabetic and other pharmacologic and biological activities of penta-galloyl-glucose. Pharm Res 26(9):2066-80.
  • Mendonca, P et al (2017). The attenuating effects of 1,2,3,4,6 penta-O-galloyl-β-d-glucose on inflammatory cytokines release from activated BV-2 microglial cells. J Neuroimmunol 305:9-15.
  • Tseeleesuren, D et al (2018). 1,2,3,4,6-Penta-O-Galloyl-Beta-D-Glucopyranoside Inhibits Proliferation of Multiple Myeloma Cells Accompanied with Suppression of MYC Expression. Front Pharmacol 9:65.

Solubility

Stability

Further Information


Datasheets

Specification: View
MSDS: View

1,2,3,4,6-Penta-O-galloyl-b-D-glucopyranose

CAS No:
14937-32-7
Synonyms:
Pentagalloylglucose
PGG
MDL No:
MFCD03788860
Chemical Formula:
Molecular Weight:
940.68
Product Structure
References:
1. Zhang, J et al (2009). Anti-cancer, anti-diabetic and other pharmacologic and biological activities of penta-galloyl-glucose. Pharm Res 26(9):2066-80.
2. Mendonca, P et al (2017). The attenuating effects of 1,2,3,4,6 penta-O-galloyl-β-d-glucose on inflammatory cytokines release from activated BV-2 microglial cells. J Neuroimmunol 305:9-15.
3. Tseeleesuren, D et al (2018). 1,2,3,4,6-Penta-O-Galloyl-Beta-D-Glucopyranoside Inhibits Proliferation of Multiple Myeloma Cells Accompanied with Suppression of MYC Expression. Front Pharmacol 9:65.
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