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BA165146
BIO-X

APD 371 NEW

A selective cannabinoid receptor type 2 (CB2) agonist. Commonly, CB2 agonists induce receptor internalization, which results in desensitization and tachyphylaxis. However, APD 371 mediates efficient recycling of internalized receptors back to the plasma membrane and thus sustains analgesic effects, upon subchronic treatment, in an osteoarthritis pain model in vivo. 

Technical Data

CAS No: 1268881-20-4
Synonyms: Olorinab
Product Code: BA165146
Chemical Formula: C18H23N5O3
Molecular Weight: 357.41

References


  • Han S et al (2017). Discovery of APD371: Identification of a Highly Potent and Selective CB2 Agonist for the Treatment of Chronic Pain. ACS Med Chem Lett 8(12):1309-1313.

Solubility

Stability

Further Information


Datasheets

Specification: View
MSDS: View

APD 371 - Bio-X

CAS No:
1268881-20-4
Synonyms:
Olorinab
Chemical Formula:
Molecular Weight:
357.41
Product Structure
References:
1. Han S et al (2017). Discovery of APD371: Identification of a Highly Potent and Selective CB2 Agonist for the Treatment of Chronic Pain. ACS Med Chem Lett 8(12):1309-1313.
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