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BS164399

Sertraline hydrochloride - Bio-X

A serotonin reuptake inhibitor that is used as an antidepressant agent. Has no modulatory actions on α-adrenergic and histaminergic receptors and mildly inhibits dopamine reuptake. A potential treatment for reducing alcohol intake. Suppresses proliferation and induces expression of AP-2α in neural crest stem cells.

Technical Data

CAS No: 79559-97-0
Synonyms: (1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine, hydrochloride; Sertraline HCl
Product Code: BS164399
MDL No: MFCD00895772
Chemical Formula: C17H18Cl3N
Molecular Weight: 342.69

References


  • Higley J et al (1998). The serotonin reuptake inhibitor sertraline reduces excessive alcohol consumption in nonhuman primates: effect of stress. Neuropsychopharmacology 18(6):431-43.
  • Sanchez C et al (2014). A comparative review of escitalopram, paroxetine, and sertraline: Are they all alike? Int Clin Psychopharmacol 29(4):185-96.
  • Vichier-Guerre C et al (2017). Impact of selective serotonin reuptake inhibitors on neural crest stem cell formation. Toxicol Lett 281:20-25

Solubility

Stability

Further Information


Datasheets


Sertraline hydrochloride - Bio-X

CAS No:
79559-97-0
Synonyms:
(1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine, hydrochloride
Sertraline HCl
MDL No:
MFCD00895772
Chemical Formula:
Molecular Weight:
342.69
Product Structure
References:
1. Higley J et al (1998). The serotonin reuptake inhibitor sertraline reduces excessive alcohol consumption in nonhuman primates: effect of stress. Neuropsychopharmacology 18(6):431-43.
2. Sanchez C et al (2014). A comparative review of escitalopram, paroxetine, and sertraline: Are they all alike? Int Clin Psychopharmacol 29(4):185-96.
3. Vichier-Guerre C et al (2017). Impact of selective serotonin reuptake inhibitors on neural crest stem cell formation. Toxicol Lett 281:20-25

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