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BG166813

GNE 6776 - Bio-X

Specific inhibitor of the ubiquitin specific protease-7 (USP7), which is a validated deubiquitinase of the E3 ubiquitin-protein ligase MDM2. The compound inhibits the USP7 deubiquitinase activity by binding to acidic amino acid residues important for the interaction with ubiquitin. Induces tumor cell death and enhances cytotoxicity of chemotherapeutic agents.

Technical Data

CAS No: 2009273-71-4
Product Code: BG166813
Chemical Formula: C20H20N4O2
Molecular Weight: 348.40

Literature


  • Kategaya L et al., (2017). USP7 small-molecule inhibitors interfere with ubiquitin binding. Nature 550(7677):534-538.

Solubility

Stability

Further Information


Datasheets


GNE 6776 - Bio-X

CAS No:
2009273-71-4
Chemical Formula:
Molecular Weight:
348.40
Product Structure
References:
1. Kategaya L et al., (2017). USP7 small-molecule inhibitors interfere with ubiquitin binding. Nature 550(7677):534-538.

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