Availability
0
Your Basket is Empty
BG166813
BIO-X

GNE 6776

Specific inhibitor of the ubiquitin specific protease-7 (USP7), which is a validated deubiquitinase of the E3 ubiquitin-protein ligase MDM2. The compound inhibits the USP7 deubiquitinase activity by binding to acidic amino acid residues important for the interaction with ubiquitin. Induces tumor cell death and enhances cytotoxicity of chemotherapeutic agents.

Technical Data

CAS No: 2009273-71-4
Synonyms: 6'-Amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-[3,3'-bipyridine]-6-carboxamide
Product Code: BG166813
MDL No: MFCD31657364
Chemical Formula: C20H20N4O2
Molecular Weight: 348.40

References


  • Kategaya L et al., (2017). USP7 small-molecule inhibitors interfere with ubiquitin binding. Nature 550(7677):534-538.

Solubility

Stability

Further Information


Datasheets

Specification: View
MSDS: View

CAS No:
2009273-71-4
Synonyms:
6'-Amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-[3,3'-bipyridine]-6-carboxamide
MDL No:
MFCD31657364
Chemical Formula:
Molecular Weight:
348.40
Product Structure
References:
1. Kategaya L et al., (2017). USP7 small-molecule inhibitors interfere with ubiquitin binding. Nature 550(7677):534-538.
Click for Specification
Click for MSDS

For requirements greater than the catalogue prepacks email: enquiries@carbosynth.com

Custom Synthesis

For custom synthesis or special requests email: enquiries@carbosynth.com, call +44 (0)1635 578444 or fill out our contact form

Please Wait...