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FB19001

Bosentan

Endothelin receptor antagonist; vasodilator

Technical Data

CAS No: 147536-97-8,157212-55-0
Synonyms: 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzenesulfonamide; p-tert-Butyl-N-[6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl]benzenesulfonamide; Actelion
Product Code: FB19001
MDL No: MFCD00867375
Chemical Formula: C27H29N5O6S
Molecular Weight: 551.62

Literature

References
  • Clozel, M., et al., J. Pharmacol. Exp. Ther., 270, 228 (1994)
  • Gutsch, G., et al., Cardiovasc. Drugs Ther., 10, 717 (1996)
  • Weber, C., et al., Clin Pharmacol. Ther., 60, 124 (1996)
  • Krum, H., et al., N. Engl. J. Med., 338, 784 (1998)

Solubility

Stability

Datasheets

Specification: View
MSDS: View

Bosentan

CAS No:
147536-97-8,157212-55-0
Synonyms:
4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzenesulfonamide
p-tert-Butyl-N-[6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl]benzenesulfonamide
Actelion
MDL No:
MFCD00867375
Chemical Formula:
Molecular Weight:
551.62
Product Structure
References:
1. Clozel, M., et al., J. Pharmacol. Exp. Ther., 270, 228 (1994)
2. Gutsch, G., et al., Cardiovasc. Drugs Ther., 10, 717 (1996)
3. Weber, C., et al., Clin Pharmacol. Ther., 60, 124 (1996)
4. Krum, H., et al., N. Engl. J. Med., 338, 784 (1998)
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