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BN164083

NGI1 - Bio-X NEW

A cell permeable inhibitor of oligosaccharyltransferase that interferes with the transfer of mature glycan precursors to recipient proteins. Causes reduced proliferation, G1 arrest and senescence in EGFR- and FGFR-dependent non-small-cell lung carcinoma (NSCLC) cells.

Technical Data

CAS No: 790702-57-7
Product Code: BN164083
Chemical Formula: C17H22N4O3S2
Molecular Weight: 394.51

References


  • Lopez-Sambrooks C et al (2016). Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells. Nat Chem Biol 12(12):1023-1030.
  • Puschnik AS et al (2017). A Small-Molecule Oligosaccharyltransferase Inhibitor with Pan-flaviviral Activity. Cell Rep 21(11):3032-3039.

Solubility

Stability

Further Information


Datasheets

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NGI1 - Bio-X

CAS No:
790702-57-7
Chemical Formula:
Molecular Weight:
394.51
Product Structure
References:
1. Lopez-Sambrooks C et al (2016). Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells. Nat Chem Biol 12(12):1023-1030.
2. Puschnik AS et al (2017). A Small-Molecule Oligosaccharyltransferase Inhibitor with Pan-flaviviral Activity. Cell Rep 21(11):3032-3039.
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