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BL163740

LF3 - Bio-X NEW

A potent inhibitor of Wnt/β-catenin signalling pathway that interferes with β-catenin/TFC4 interaction. Reduces growth and motility of colon cancer cells. Inhibits self-renewal, whilst inducing differentiation in cancer stem cells.

Technical Data

CAS No: 664969-54-4
Synonyms: N-​[4-​(Aminosulfonyl)​phenyl]​-​4-​(3-​phenyl-​2-​propen-​1-​yl)​-1-​Piperazinecarbothioa​mide
Product Code: BL163740
Chemical Formula: C20H24N4O2S2
Molecular Weight: 416.56

Literature


  • Fang L et al (2016). A Small-Molecule Antagonist of the β-Catenin/TCF4 Interaction Blocks the Self-Renewal of Cancer Stem Cells and Suppresses Tumorigenesis. Cancer Res 76(4):891-901.

Solubility

Stability

Further Information


Datasheets

Specification: View
MSDS: View

LF3 - Bio-X

CAS No:
664969-54-4
Synonyms:
N-​[4-​(Aminosulfonyl)​phenyl]​-​4-​(3-​phenyl-​2-​propen-​1-​yl)​-1-​Piperazinecarbothioa​mide
Chemical Formula:
Molecular Weight:
416.56
Product Structure
References:
1. Fang L et al (2016). A Small-Molecule Antagonist of the β-Catenin/TCF4 Interaction Blocks the Self-Renewal of Cancer Stem Cells and Suppresses Tumorigenesis. Cancer Res 76(4):891-901.
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