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BF167835
BIO-X

Fasentin NEW

Inhibitor of glucose uptake via GLUT1 and GLUT4 transporters, promoting intracellular glucose deprivation. The compound is a chemical sensitizer to the FAS cell death receptor and is able to break down the resistance of caspase activation. It has potential for anti-cancer therapy as it modulates the Warburg effect in cancer cell lines.

Technical Data

CAS No: 392721-37-8
Product Code: BF167835
MDL No: MFCD01001285
Chemical Formula: C11H9ClF3NO2
Molecular Weight: 279.64

References


  • Wood et al. (2008). A novel inhibitor of glucose uptake sensitizes cells to FAS-induced cell death. Molecular Cancer Therapeutics 7(11).
  • Akins et al. (2018). Inhibition of Glycolysis and Glutaminolysis: An Emerging Drug Discovery Approach to Combat Cancer. Current Topics in Medicinal Chemistry 18:494-504.

Solubility

Stability

Further Information


Datasheets

Specification: View
MSDS: View

CAS No:
392721-37-8
MDL No:
MFCD01001285
Chemical Formula:
Molecular Weight:
279.64
Product Structure
References:
1. Wood et al. (2008). A novel inhibitor of glucose uptake sensitizes cells to FAS-induced cell death. Molecular Cancer Therapeutics 7(11).
2. Akins et al. (2018). Inhibition of Glycolysis and Glutaminolysis: An Emerging Drug Discovery Approach to Combat Cancer. Current Topics in Medicinal Chemistry 18:494-504.
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