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BM163575
BIO-X

MCC 950 sodium NEW

Inhibitor of NLRP3 inflammasome and suppressor of the inflammatory cytokine IL-1β secretion. The compound was tested in diabetic mice and was shown to decrease the incidence of cardiac arrythmias, which are common secondary complications in diabetes mellitus. MCC 950 has potential to reverse diabetes-induced pathologies in cardiac electrophysiology.

Technical Data

CAS No: 256373-96-3
Synonyms: N-​[[(1,​2,​3,​5,​6,​7-​Hexahydro-​s-​indacen-​4-​yl)​amino]​carbonyl]​-​4-​(1-​hydroxy-​1-​methylethyl)​-2-​furansulfonamide sodium; CP-456773 sodium; CRID3 sodium
Product Code: BM163575
Chemical Formula: C20H23N2O5S·Na
Molecular Weight: 426.46

References


  • Monnerat et al (2016). Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice. Nature Communications 7:1334.

Solubility

Stability

Further Information


Datasheets

Specification: View
MSDS: View

MCC 950 sodium - Bio-X

CAS No:
256373-96-3
Synonyms:
N-​[[(1,​2,​3,​5,​6,​7-​Hexahydro-​s-​indacen-​4-​yl)​amino]​carbonyl]​-​4-​(1-​hydroxy-​1-​methylethyl)​-2-​furansulfonamide sodium
CP-456773 sodium
CRID3 sodium
Chemical Formula:
Molecular Weight:
426.46
Product Structure
References:
1. Monnerat et al (2016). Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice. Nature Communications 7:1334.
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