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Other Targets

These compounds act on targets other than 7-TM receptors, nuclear receptors, enzymes, ion channels, protein interactions, transporters and do not have DNA crosslinking activity. Other targets include imidazoline receptors and sigma receptors. This list of compounds also includes products with known applications, but with unknown or non-specific mode of action.

Code Cas No Product Description
FA158666 59-53-0

N-Acetyl-DL-penicillamine

Protective agent against mercuric chloride poisoning
FA01736 90058-29-0

Alaptide

Nootropic agent; affects dopaminergic system
FA17279 26750-81-2

Alibendol

Anti-spasmodic, choleretic and cholekinetic agent
FA17334 645-05-6

Altretamine

Alkylating agent; cytotoxic; antineoplastic
FA17353 20537-88-6

Amifostine

Radio- and chemoprotective agent
FA17548 86029-68-7

2-Amino-4,5,6,7,8-pentahydrothiazolo[5,4-d]azepine

Talipexole metabolite
FA17935 102-14-7

4-Anilino-4-oxobutanoic acid

Vorinostat metabolite
FA17994 88495-63-0

Artesunate

Prodrug of dihydroartemisin (DHA); antimalarial
FB18131 80573-04-2

Balsalazide

Prodrug of 5-aminosalicylic acid; anti-inflammatory
FB18146 138356-09-9

BD 1008 dihydrobromide

Sigma (σ) receptor antagonist
FB18147 150208-28-9

BD 1063

Antagonist of σ1 receptor
FB18170 19428-14-9

Benproperine phosphate

Anti-tussive agent
FB18200 68-90-6

Benziodarone

Uricosuric agent
BB162705 76455-48-6

4-Bromo-A23187

Non-fluorescent Ca2+ ionophore; for calibrating fluorescent Ca2+ probes
FB19345 65002-17-7

Bucillamine

Potential treatment for gout and rheumatoid arthritis
BC162800 577696-37-8

Cardionogen 1

Promotes cardiomyocyte generation
BC164299 27724-96-5
34675-84-8

Cetraxate hydrochloride

Anti-ulcerative agent
FC20409 94-20-2

Chlorpropamide

Hypoglycemic agent
FC20416 95-25-0
202-403-9

Chlorzoxazone

Muscle relaxant; treats muscle spasms
BC164318 4291-63-8

Cladribine

Deoxyadenosine analog resistant to adenosine deaminase
BC167259 130-26-7

Clioquinol

Anti-infective agent against diarrhoea; chelating application for Alzheimer’s
FC161383 71923-34-7

Clodoxopone

Hypolipidemic agent
BC166450

CMP 98

Negative control for CM11; no effect on VHL E3 ubiquitin ligase
FC161379 4366-18-1

Coumetarol

Anti-coagulant
EC70361 6190-45-0

Creatine phosphate disodium salt hexahydrate

Phosphate reservoir in muscles, aiding conversion of ADP to ATP
FC138959 172430-48-7

CVT 3369

Metabolite of ranolazine
FB20882 201530-41-8

Deferasirox

Tridentate iron chelator
FD64999 554435-83-5

Deferasirox Fe3+ Chelate

Iron chelator
FD21050 148-51-6

4-Deoxypyridoxine hydrochloride

Vitamin B6 antimetabolite
BE162326 95-04-5

Ectylurea

Sedative; anti-convulsant
BE164429 7414-83-7

Etidronate disodium

Atherosclerotic plaque inhibitor; anti-bone resorptive therapy
FE65021 52479-85-3

Exifone

Mildly inhibits tau protein fibril formation; enhances cognitive function
BF162803 2719-05-3

FH 1

Promotes differentiation of iPSCs into hepatocytes
NF32352 9001-32-5

Fibrinogen - from bovine plasma

Required for blood coagulation
FF35415 27072-45-3
3326-32-7

Fluorescein isothiocyanate

Labeling reagent for fluorescent-based applications
FG40726 51-77-4

Gefarnate

Used to treat gastrointestinal ulcers
FG138110 147245-92-9

Glatiramer acetate

Used to treat multiple sclerosis; anti-inflammatory
BG162807 49557-75-7

Glycyl-L-histidyl-L-lysine

Copper-binding growth factor
BI162777 1160927-48-9

IDE 1

Inducer of endoderm formation in embryonic stem cells
BI162799 1136466-93-7

IDE 2

Inducer of endoderm formation in embryonic stem cells
BI164565 58186-27-9

Idebenone

Used for treatment of Alzheimer's disease and Friedreich's ataxia
FI148966 6961-46-2

Idrocilamide

Muscle relaxant; anti-inflammatory
FI24595 606-17-7

Iodipamide

Ionic dimeric contrast agent for diagnostic imaging of the liver
FI07802 35212-22-7

Ipriflavone

Isoflavone; inhibits bone loss
FI63880 4214-72-6

Isopropyl-pyrimidin-2-yl-amine

Causes allergic hepatitis
OK146493 214491-07-3

Kotalanol

BK162779 1118807-13-8

KY 02111

Inhibits Wnt singalling; promotes differentiatoin of hPSCs to cardiomyocytes
FM25114 19767-45-4

Mesna

Reduces toxic effects of chemotherapeutic agents on urinary tract
BM166959 1443414-10-5

Metarrestin

Perinuclear compartment (PNC) inhibitor; anti-cancer agent; inhibits metastasis
FM25909 53179-13-8

5-Methyl-N-phenyl-2-1H-pyridone

Anti-inflammatory, anti-oxidant and anti-fibrotic agent
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