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7-TM Receptors

A large proportion of commercially-available drugs target seven transmembrane (7-TM) receptors, of which a selection is offered by Carbosynth that are listed below. 7-TM receptors are the largest superfamily of cell surface receptors, also known as G-protein-coupled receptors (GPCRs). These receptors transduce signals from the extracellular space to the cytoplasm, via their transmembrane domains. Based on sequence homology, 7-TM receptors are classed into 6 groups: Class A (rhodopsin-like), Class B (secretin receptor family), Class C (metabotropic glutamate), Class D (fungal mating pheromone receptors), Class E (cyclic AMP receptors) and Class F (frizzled/smoothened).

Code Cas No Product Description
FA103508 871224-64-5

Almorexant

BB163663 2117404-84-7

BAY 677

FC156780 21898-19-1

Clenbuterol HCl

FE162098 1173755-55-9

Eteplirsen

FL65067 53179-11-6

Loperamide

μ-opioid receptor agonist; calcium channel inhibitor; anti-diarrheal
FM160701 1019-45-0

5-Methoxy-N,N-dimethyltryptamine

BM165560 2427-79-4

5-Methoxy-N,N-dimethyltryptamine HCl

FM65092 103775-10-6

Moexipril HCl

BN166402 26159-34-2

(S)-Naproxen Sodium

COX1/2 inhibitor; nonsteroidal anti-inflammatory drug
FN26278 479347-86-9
118876-58-7

NBQX disodium

FR103488 841290-80-0

R-406 free base

BR161263 9017-74-8

Recombinant Enterokinase

BT163656 214782-56-6

Teriflunomide isomer E

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