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Custom Synthesis

Turn Ideas into Molecules

Carbosynth provide effective solutions tailored to meet your needs and offer custom synthesis as well as FTE services. Our synthetic laboratories operate from a modern well equipped facility near Oxford, UK. Our scientists are skilled in design and synthesis of complex multi-step reaction schemes. We handle from mg to 100 g scale and are able to transfer technology to our bulk manufacturing plant. 

 Custom synthesis - Laboratory

 

Our team is composed of highly qualified chemists and analysts. The technical staff is educated predominantly to PhD level in organic chemistry with extensive industry experience in carbohydrates, imino sugars, glycosylation, nucleosidation and medicinal chemistry.  

  

We specialise in the following chemistries and services:Custom synthesis - Equipment horizontal

  • Functionalised carbohydrate building blocks and derivatives
  • Oligosaccharide synthesis
  • Nucleosides, dinucleotides and analogues
  • Heterocyclic chemistry
  • Natural product synthesis
  • Impurities and metabolites
  • Protein conjugation, biotin and click linkers
  • Fluorination, phosphorylation and sulphation chemistry
  • High purity complex products
  • Synthetic route development

 

 

Our state of the art synthetic labs are equipped with modern preparative and analytical tools:Custom synthesis - Equipment UPLC

  • Medium Pressure Liquid Chromatography (MPLC)
  • Size exclusion chromatography (SEC)
  • Preparative HPLC
  • Microwave synthesis system
  • Automated purification systems (Puriflash, Biotage and Companion)
  • Rotavapors and Freeze Dryers
  • Nuclear magnetic resonance (NMR) 400 MHz with broadband probe
  • Liquid Chromatography–Mass Spectrometry (LC-MS)
  • Ultra Performance Liquid Chromatography (UPLC)
  • Ion Chromatography (IC) system Dionex
  • Gas chromatography (GC)
  • Inductively Coupled Plasma (ICP) for metal ion analysis
  • Polarimeter for optical rotation measurments

 

 

 High quality, on-time delivery and confidentiality are at the core of our service.

 

Contact us for your custom synthesis requirements

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